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The STEP-HFpEF trial randomised 529 patients with obesity (BMI 30 kg/m 2 ), HFpEF (left ventricular ejection fraction [LVEF] 45%) and New York Heart Association (NYHA) Class II symptoms to once-weekly subcutaneous semaglutide 2.4 mg or placebo
These limitations necessitate exploring alternative therapeutic options
V.MikiT.et al (2011)
The interlinked biomarkers and pathways will provide better understanding between PCa and obesity interactions
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